Intellectual alienation
Existential depression
Despair that comes from seeing clearly rather than from a loss: death, meaninglessness, isolation, and freedom, the four “ultimate concerns” of Irvin Yalom’s existential therapy. James Webb described it in gifted people who hit these questions early and alone, at eight or twelve, without the life experience or company to hold them. It isn’t a DSM diagnosis, but it can turn into one.
Practitioner wisdom