discarded research
Papers we reviewed and did not cite — and the reason. Most are class mismatches, not bad studies.
Our rule is in our method: we cite the deep-penetrating near-infrared class delivered through the nose for the brain. A paper can be perfectly good and still not be that class. When it isn't, we set it aside here rather than quietly drop it.
| Paper | Reason we don't cite it |
|---|---|
| Alves AC, et al. Low-level laser on joint inflammation. Lasers in Medical Science, 2013. | Surface, joint — not brain, not through-nose. |
| Chow RT, et al. LLLT for neck pain. The Lancet, 2009. | Surface, musculoskeletal class. |
| Gomes CF, et al. PBM for diabetic wound healing. Lasers in Medical Science, 2015. | Surface, skin — different delivery class. |
| Leal-Junior EC, et al. Phototherapy, exercise performance. Lasers in Medical Science, 2015. | Surface / muscle class. |
| Loeb LM, et al. LLLT vs BT-A in chronic migraine. Photomedicine and Laser Surgery, 2018. | Local/surface — not the intranasal brain class. |
| Ohshiro T. LLLT in infertility. Laser Therapy, 2012. | Local, non-cranial class. |
| Sene-Fiorese M, et al. Phototherapy, body composition. Lasers in Medical Science, 2015. | Surface class. |
| Armagan O, et al. LLLT in fibromyalgia. Rheumatology International, 2006. | Surface, musculoskeletal class. |
| Endo M, et al. 830 nm laser for infertility. Laser Therapy, 2020. | Local, non-cranial class. |
| Ferraresi C, et al. LLLT on muscle. Photonics & Lasers in Medicine, 2012. | Surface / muscle class. |
| Fukuda TY, et al. LLLT for diabetic neuropathy. Lasers in Surgery and Medicine, 2013. | Surface / peripheral class. |
| da Silveira Campos RM, et al. PBM and body composition. Obesity Surgery, 2018. | Surface class. |
| Alfredo PP, et al. LLLT in knee osteoarthritis. Clinical Rehabilitation, 2012. | Surface, joint class. |
| Bussadori SK, et al. LLLT for migraine. Cranio, 2015. | Local/surface class. |
| Mokmeli S, Vetrici M. LLLT for COVID cytokine storm. Canadian Journal of Respiratory Therapy, 2020. | Systemic/surface class. |
| Begum R, et al. NIR in aged Drosophila. Biology Letters, 2022. | Non-human; not the through-nose brain class. |
General photobiomodulation mechanism reviews (e.g. Hamblin) are used for background on how light acts on mitochondria — they are not class-specific evidence, so they are scoped to mechanism only.
Our research method — the class rule.
Research at dreamlab.